“Cognitive Effects of Risperidone in Children with Autism & Irritable Behavior” Article Review

Abstract

Week 3 Assignment asks the following: “Read the article “Cognitive Effects of Risperidone in Children with Autism and Irritable Behavior”, and identify the research questions and/or hypotheses as they are stated. Consider the following questions: What are the variables (sample sizes, population, treatments, etc.)? How was the analysis of variance used in this article (and what type of ANOVA was used)? Determine what question(s) the authors are trying to answer by doing this research. Determine the hypothesis being tested and the concepts that were applied in this process. Evaluate the article and critique the statistical analysis employed in the study. Would you have included more and/or different variables?  Examine the assumptions and limitations of the statistical study. What would you have done differently in this case? Identify how the authors applied statistical testing to the problem. Interpret the findings of the author(s) using statistical concepts”.

Keywords: autism, behavior, variables

Today autism is one of the fastest-growing developmental disorders in the United States, which affects one in sixty-eight children on average (Autism Speaks Inc., 2016). Unfortunately, there is no medical detection or cure for this mental disorder, but significant strides have been made in its treatment and diagnosing. Autism can be found in children all around the world, and, as statistics shows, nearly 1.5 million individuals in the U.S. may be affected with this developmental disorder. It influences a child’s social interaction, language and behavior. This developmental disorder can affect many areas of a person’s life, thus it is crucially important to know all possible risks and benefits of medications for autism.

In the article, “Cognitive Effects of Risperidone in Children with Autism and Irritable Behavior”, researchers explore the effects of the popular drug (Risperidone) on children with autism and irritable behavior. Thus, the hypothesis is being tested in this study is what are the effects of Risperidone on children 5-17 years with autism and severe behavioral disturbances. Children were randomly assigned to this drug (0.5 to 3.5 mg/day) or placebo for eight weeks. Researchers implemented statistical analysis utilizing the analysis of variance (ANOVA) because the study involved two independent variables and more than one group of subjects. I think that ANOVA was the best procedure for this research. A total of 101 participants were involved (52 were assigned to placebo, and 49 to Risperidone). Researchers accurately accessed the variances between the test subjects (who took part in the extended trial and who did not) and linked the demographical clinical features by via-tests (continuous variables) and chi-square tests (categorical variables). I think that the study was accurately conducted and there were no need to add other possible variables. I would not have done anything differently during the study. The conclusion of the study suggests that “Risperidone given to children with autism at doses up to 3.5 mg for up to 8 weeks appears to have no detrimental effect on cognitive performance” (Aman, 2008). The 29 boys and 9 girls with autism and severe behavioral disturbance and a mental age nearly 18 months did not show any decrease in their performance occurred with Risperidone. In this paper, I have determined what questions the authors were trying to answer by doing the research, defined the specific hypothesis that was being tested, and the concepts that were applied during the study. I also evaluated the study and statistical analysis that was implemented in the research, and answered whether or not I would have added any more or any different variables that the ones already included by the researchers. Finally, I have interpreted the findings of the research.

Autism still remains a disability that can influence different areas of an individual’s life. According to National Institutes on Health (2016), its severity and symptoms vary significantly, but children generally have some problems in social interaction, language and behavior. Being that so many individuals with this mental disorder have difficulties in different areas of their life, it is crucially important to know all possible risks and benefits of medications for autism.  

References:

Aman, M. G., Hollway, J. A., McDougle, C. J., Scahill, L., Tierney, E., McCracken, J. T., . . .Posey, D. J. (2008). Cognitive Effects of Risperidone in Children with Autism and Irritable Behavior. Journal of Child and Adolescent Psychopharmacology, 18(3), 227-236

Autism Speaks Inc. (2016). Facts about Autism. Retrieved from  https://www.autismspeaks.org/what-autism/facts-about-autism

National Institutes on Health (2016). Autism Spectrum Disorder: Communication Problems in   Children. Retrieved from NIDCD https://www.nidcd.nih.gov/health/autism-spectrum- disorder-communication-problems-children

The terms offer and acceptance. (2016, May 17). Retrieved from

[Accessed: January 20, 2022]

"The terms offer and acceptance." freeessays.club, 17 May 2016.

[Accessed: January 20, 2022]

freeessays.club (2016) The terms offer and acceptance [Online].
Available at:

[Accessed: January 20, 2022]

"The terms offer and acceptance." freeessays.club, 17 May 2016

[Accessed: January 20, 2022]

"The terms offer and acceptance." freeessays.club, 17 May 2016

[Accessed: January 20, 2022]

"The terms offer and acceptance." freeessays.club, 17 May 2016

[Accessed: January 20, 2022]

"The terms offer and acceptance." freeessays.club, 17 May 2016

[Accessed: January 20, 2022]
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